1 2 3 4 5 6 Metabotropic Glutamate Receptors and Glutamate Transporters Shape Transmission at 7 the Developing

11 12 13 14 Department of Neurology, F.M. Kirby Neurobiology Center, Children’s Hospital, Boston, 15 300 Longwood Avenue, Boston, MA 02115 16 and 17 Program in Neuroscience, Harvard Medical School, 18 220 Longwood Avenue, Boston, MA 02115 19 20 21 § these authors contributed equally to this work 22 23 *To whom correspondence should be addressed: 24 Phone: 617-919-2685, Fax: 617-730-0242 25 [email protected] 26 27 28 Abbreviated Title: mGluRs and Transporters in the Developing LGN 29 30 Number of Figures: 6 31 32 Number of words: Abstract: 238, Introduction: 516, Discussion: 1487 33 (Abstract+Intro+discussion=2241/2250) 34 35 Financial Interests or Conflicts of Interest: none 36 37 Acknowledgements: We thank A. Thompson, S. Park, J. Leffler, M. Do, T. Soulier, X. Liu for 38 helpful discussions of the experiments and manuscript. This work was supported by the NEI 39 T32 EY007110 to JLH, F31 NS044793 to EBE, NIH F31 NS048630 to BMH and RO1EY013613 40 to CC and the Children’s Hospital Boston Intellectual and Developmental Disabilities Research 41 Center NICHD P01HD18655. 42 Articles in PresS. J Neurophysiol (October 17, 2012). doi:10.1152/jn.00897.2012